Choose the brand aligned with your industry so we can best serve your needs.
For researchers, scientists, and technical professionals: Your one-stop shop for the complete range of laboratory, production, and safety products and services.
Assays, reagents, kits, and other assorted products used to detect cellular apoptosis, determine the activity levels of caspase or cathepsin, or identify similar cellular activity.
Small and Specialty Supplier Partner Small and/or specialty supplier based on Federal laws and SBA requirements. Learn More
Caspases are cysteine proteases that cleave C-terminal aspartic acid residues on their substrate molecules This gene is most highly related to members of the ICE subfamily of caspases that process inflammatory cytokines In rodents the homolog of this gene mediates apoptosis in response to endoplasmic reticulum stress However in humans this gene contains a polymorphism for the presence or absence of a premature stop codon The majority of human individuals have the premature stop codon and produce a truncated non-functional protein The read-through codon occurs primarily in individuals of African descent and carriers have endotoxin hypo-responsiveness and an increased susceptibility to severe sepsis Several alternatively spliced transcript variants have been noted for this gene
Encompass Procurement Services Non-distribution item offered as a customer accommodation; additional freight charges may apply. Learn More